The Last Peptide

Every peptide calculator

Each page presets typical vial sizes and dose ranges for that peptide, and states its FDA status before any numbers appear.

Metabolic & Weight Management 17

Semaglutide

A GLP-1 receptor agonist prescribed for type 2 diabetes and chronic weight management, dosed once weekly.

FDA-approved
Tirzepatide

A dual GIP and GLP-1 receptor agonist prescribed for type 2 diabetes and chronic weight management, dosed once weekly.

FDA-approved
Retatrutide

An investigational triple receptor agonist studied for obesity and metabolic disease. Not available as an approved medicine.

AOD-9604

A fragment of human growth hormone originally investigated for obesity, which failed to meet endpoints in clinical trials.

5-Amino-1MQ

A small-molecule NNMT inhibitor studied for effects on fat cell metabolism. Not a peptide, and not an approved drug.

Adipotide

An investigational peptide designed to destroy the blood vessels feeding white fat. Studied mainly in animals, with early human work halted.

AICAR

An AMPK activator studied as an 'exercise mimetic.' Not a peptide, prohibited in sport, and not approved for human use.

Cagrilintide

An investigational long-acting amylin analog for weight management, studied alone and in combination with semaglutide.

Cagrilintide + Semaglutide

The investigational fixed combination of the amylin analog cagrilintide with the GLP-1 agonist semaglutide, developed for greater weight loss.

L-Carnitine

A naturally occurring compound involved in fat transport into mitochondria, available as an oral supplement and an injectable prescription product.

Mazdutide

An investigational dual GLP-1 and glucagon receptor agonist developed for weight management and metabolic disease.

Methionine + Choline + L-Carnitine + Dexpanthenol

A compounded 'lipotropic' injection blend of nutrients marketed for weight loss. Evidence for meaningful fat loss is weak.

MIC (Lipo-C with B12)

A lipotropic injection blend of methionine, inositol, and choline, often combined with B12 or carnitine. Evidence for weight loss is weak.

MOTS-c

A mitochondria-encoded peptide studied for effects on metabolism and insulin sensitivity. Human evidence is early.

Retatrutide + Cagrilintide

An investigational pairing of the triple agonist retatrutide with the amylin analog cagrilintide. No combined product is approved.

Retatrutide + Tirzepatide

An unstandardized supplier blend of retatrutide and tirzepatide. No such combined product is approved or studied.

Survodutide

An investigational dual GLP-1 and glucagon receptor agonist studied for obesity and metabolic liver disease (MASH).

Recovery & Tissue Repair 10

Growth Hormone Axis 16

Ipamorelin

A selective growth hormone secretagogue often discussed together with CJC-1295.

CJC-1295

A GHRH analog discussed in growth hormone secretagogue protocols, frequently paired with ipamorelin.

Sermorelin

A GHRH analog historically used in diagnostic testing and now dispensed largely through compounding pharmacies.

Tesamorelin

A GHRH analog approved to reduce excess abdominal fat in people with HIV-associated lipodystrophy.

FDA-approved
CJC-1295 No DAC + Ipamorelin

The most common growth-hormone secretagogue pairing, combining a GHRH analog with a ghrelin-mimetic. Neither component is approved; the blend is unregulated.

CJC-1295 With DAC

The long-acting form of CJC-1295, bound to a drug affinity complex that extends its half-life to about a week. Not approved; prohibited in sport.

Follistatin

A protein that binds and neutralizes myostatin, studied for muscle growth. Investigated via gene therapy; peptide use is unstudied and risky.

GHRP-2

A ghrelin-mimetic growth hormone secretagogue, one of the earlier and less selective of its class. Not approved; prohibited in sport.

GHRP-6

A ghrelin-mimetic growth hormone secretagogue notable for strongly stimulating appetite. Not approved; prohibited in sport.

Hexarelin

A potent ghrelin-mimetic growth hormone secretagogue, among the strongest of its class but with receptor desensitization over time. Not approved.

HGH 191AA

Recombinant human growth hormone — the full 191-amino-acid hormone. A prescription drug for specific deficiency states; widely misused.

FDA-approved
IGF-1 LR3

A long-acting modified form of IGF-1 studied for anabolic effects. A research compound with no approved use and real hypoglycemia risk.

IGF-DES

A truncated, fast-acting form of IGF-1 with reduced binding-protein interference. A research compound with no approved use and hypoglycemia risk.

MGF

A splice variant of IGF-1 produced by muscle in response to mechanical damage, studied for muscle repair. No human trials.

PEG-MGF

A PEGylated (longer-acting) form of mechano growth factor, modified to extend its short half-life. No human trials.

Tesamorelin + Ipamorelin

A pairing of the approved GHRH analog tesamorelin with the secretagogue ipamorelin. Tesamorelin alone is approved; the combination is not studied.

Hormonal & Sexual Health 9

Longevity & Cellular Health 10

Cognitive & Neurological 14

Adamax

A research peptide marketed for cognitive support. There is no meaningful published evidence base for it.

Adamax-982

A supplier-branded research peptide marketed for cognitive support. There is no meaningful published evidence base for it.

Adamax-984

A supplier-branded research peptide marketed for cognitive support. There is no meaningful published evidence base for it.

Adamax-1032

A supplier-branded research peptide containing an adamantane group, marketed for cognitive support. No meaningful published evidence base.

Cerebrolysin

A mixture of peptides derived from pig brain, used in some countries for stroke and dementia. Not approved in the US; evidence is contested.

Cerebroprotein Hydrolysate

A brain-derived peptide mixture similar to Cerebrolysin, used in some countries for neurological conditions. Not approved in the US.

Cortagen

A short brain-targeted 'peptide bioregulator' marketed for cognitive support. Evidence is thin and largely regional.

Dihexa

A research peptide derived from angiotensin IV, studied for potent cognitive effects in animal models. Extremely potent; no human trials.

DSIP

A nonapeptide studied for sleep and stress effects since the 1970s. Evidence for a clear sleep-inducing effect is inconsistent.

PE-22-28

A short peptide analog studied for rapid antidepressant-like effects in animal models via TREK-1 channel blockade. No human trials.

Pinealon

A short pineal-gland-targeted 'peptide bioregulator' marketed for sleep and cognitive support. Evidence is thin and largely regional.

Selank

A synthetic heptapeptide analog of tuftsin, studied for anxiolytic effects. Used in Russia; not approved in the US.

Selank + Semax

A pairing of the anxiolytic peptide Selank with the nootropic peptide Semax. Neither is approved in the US; the combination is unstudied.

Semax

A synthetic fragment of ACTH studied for nootropic and neuroprotective effects. Used in Russia; not approved in the US.

Specialty & Other Compounds 30

ACE-031

An investigational myostatin-inhibiting protein developed for muscular dystrophy. Development was halted over safety signals.

Acetic Acid Solution

A dilute acid solution sometimes used to reconstitute certain peptides that don't dissolve well in plain water. Not a drug.

AHK-Cu

A copper-binding peptide studied for hair growth and skin, a relative of GHK-Cu. Largely cosmetic and in-vitro evidence.

Alprostadil

A prostaglandin used to treat erectile dysfunction and to keep a fetal heart vessel open in newborns. A prescription drug.

ARA-290

A peptide derived from erythropoietin, studied for nerve pain and tissue repair without the blood-thickening effects of EPO. Investigational.

Bacteriostatic Water

Sterile water with 0.9% benzyl alcohol, used to dissolve and store injectable medications. The standard reconstitution liquid.

Botulinum Toxin

A neurotoxin used medically and cosmetically to relax muscles. A prescription drug with strict handling — not a peptide for self-administration.

Crystagen

A short 'peptide bioregulator' marketed for immune support. Evidence is thin and largely regional.

Dermorphin

A potent opioid peptide originally from frog skin, with pain-relieving effects stronger than morphine in animals. Abused in horse racing; not for human use.

Eloralintide

An investigational next-generation amylin analog for weight management. Early-stage; not approved.

EPO

A hormone that stimulates red blood cell production, used to treat certain anemias. A prescription drug with serious risks in misuse.

GDF-8

The scientific name for myostatin — the body's natural brake on muscle growth. Note: myostatin inhibitors are what's studied, not myostatin itself.

Glutathione

The body's main intracellular antioxidant, given by IV and orally for various uses. Oral absorption is poor; IV use is clinical.

Hyaluronic Acid

A large sugar molecule used in skin fillers, joint injections, and topical products. Approved for specific uses; widely used cosmetically.

Insulin

A life-sustaining hormone for diabetes. A prescription drug with a narrow safety margin — dosing errors can be fatal.

LC120

A supplier-branded research compound. There is no meaningful published evidence base for it.

LC216

A supplier-branded research compound. There is no meaningful published evidence base for it.

LL-37

A human antimicrobial peptide involved in immune defense. Studied for infection and wound healing; complex immune effects, no approved use.

Lysine-Proline-Valine

The three-amino-acid sequence that makes up KPV, the anti-inflammatory fragment of alpha-MSH. See the KPV entry for the full picture.

Matrixyl

A well-established cosmetic peptide used topically for skin aging. One of the few peptides with real cosmetic-trial support.

MK-677

An oral growth-hormone secretagogue (not a peptide) studied in human trials. Investigational; raises appetite and blood sugar.

Phosphate Buffered Saline

A sterile salt-and-buffer solution used to dissolve and dilute laboratory compounds. Not a drug.

PNC-27

A research peptide studied in the lab for selectively killing cancer cells. Cell and animal work only; no human trials.

Relaxation PM

A branded supplier blend marketed for relaxation and sleep. Composition varies by supplier and is unregulated.

SLU-PP-332

A research 'exercise mimetic' that activates estrogen-related receptors to mimic exercise metabolism. Animal studies only; not a peptide.

Snap-8

A topical cosmetic peptide marketed as a 'botox-like' anti-wrinkle ingredient. Cosmetic-grade evidence only.

Testagen

A short testis-targeted 'peptide bioregulator' marketed for male hormonal support. Evidence is thin and largely regional.

Vasoactive Intestinal Peptide

A naturally occurring hormone that dilates blood vessels and airways. Studied for pulmonary hypertension and other conditions; investigational for most uses.

VIP (Vasoactive Intestinal Peptide)

The common abbreviation for vasoactive intestinal peptide — a natural hormone that dilates blood vessels and airways. See the full VIP entry.

Vitamin B12

An essential B vitamin given by injection for deficiency. Not a peptide; well established for treating true deficiency.