VIP (Vasoactive Intestinal Peptide) calculator
The common abbreviation for vasoactive intestinal peptide — a natural hormone that dilates blood vessels and airways. See the full VIP entry.
Also known as: Aviptadil, Vasoactive Intestinal Peptide acetate
FDA status — not an approved drug VIP (aviptadil) is not FDA-approved for general use. It has been studied for pulmonary hypertension and other conditions and is approved in some countries in specific forms, but most uses are investigational.
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What VIP (Vasoactive Intestinal Peptide) is
VIP is the common abbreviation for vasoactive intestinal peptide (aviptadil), a naturally occurring 28-amino-acid hormone with potent effects on blood vessels, airways, and immune function. It is studied for pulmonary hypertension and inflammatory conditions and is not FDA-approved for general use in the United States.
Research depth: 3/5 Studied in human trials for cardiopulmonary conditions; most uses investigational and not FDA-approved for general use. Human trials: Human trials for specific uses. This measures how much has been studied — counting animal and laboratory work — not whether it works for you.
How VIP (Vasoactive Intestinal Peptide) works
It binds VIP receptors (VPAC1 and VPAC2), relaxing smooth muscle to dilate blood vessels and airways and modulating immune-cell activity to reduce inflammation. These combined effects are the basis for its study in cardiopulmonary and inflammatory conditions.
VIP (Vasoactive Intestinal Peptide) side effects
Commonly reported
- Flushing and warmth
- Low blood pressure and dizziness
- Rapid heart rate
- Nausea
Serious — seek medical care
- Can cause significant drops in blood pressure — requires clinical administration
- Most uses are investigational
- Not FDA-approved for general use
This list is not exhaustive. Report anything unexpected to the clinician who prescribed it. If you have severe abdominal pain, trouble breathing, or signs of an allergic reaction, seek care the same day. See also our guide to peptide side effects by class.
A worked example
A 1 mg vial reconstituted with 2 mL of bacteriostatic water gives 0.5 mg/mL. A 100 mcg dose is then 0.2 mL — about 20 units on a 100-unit insulin syringe, giving roughly 10 doses per vial before accounting for residual volume left in the vial and syringe.
Prefer paper? Download the printable VIP (Vasoactive Intestinal Peptide) dosing chart (PDF) — every vial size and water volume in syringe units, with the same review byline as this page. All charts →
Commonly cited dose range
Figures circulating for VIP (Vasoactive Intestinal Peptide) run from 50 mcg to 400 mcg. VIP is the abbreviation for vasoactive intestinal peptide — figures reflect research reference points in micrograms. There is no established self-administered dose.
Read this as reference information, not instruction. These numbers describe what is commonly discussed, not what is right for any individual. Dose, frequency, and whether to use VIP (Vasoactive Intestinal Peptide) at all are decisions for a licensed clinician who knows your history.
Common questions
What does VIP stand for?
VIP stands for vasoactive intestinal peptide, a natural hormone that dilates blood vessels and airways. It is also called aviptadil. See the full vasoactive intestinal peptide entry for the complete detail.
Is VIP approved in the US?
Not for general use. It is approved in some countries in specific forms and studied for cardiopulmonary and inflammatory conditions, but most uses are investigational.