Selank + Semax calculator
A pairing of the anxiolytic peptide Selank with the nootropic peptide Semax. Neither is approved in the US; the combination is unstudied.
Also known as: Selank/Semax blend, Nootropic peptide blend
FDA status — not an approved drug Not FDA-approved. Neither Selank nor Semax is FDA-approved, and the combination has not been studied.
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What Selank + Semax is
Selank with Semax is a pairing of two Russian-developed peptides: Selank, an anxiolytic, and Semax, a nootropic studied for focus and cognition. The blend is marketed for calm focus. Neither component is FDA-approved, and the combination has no clinical evidence.
Research depth: 1/5 Regional data for each component, but no trials of the combination. Human trials: None for the combination. This measures how much has been studied — counting animal and laboratory work — not whether it works for you.
How Selank + Semax works
Each acts on central-nervous-system signaling: Selank appears to modulate GABA and anxiety-related neurotransmitters, while Semax is a fragment of ACTH that influences neurotrophic and dopaminergic signaling. The pairing is intended to be complementary, but the combination is unstudied.
Selank + Semax side effects
Commonly reported
- Mild nasal irritation with intranasal use
- No studies of the combination
- Effects are uncharacterized in combination
Serious — seek medical care
- No studies of the combination — interactions unknown
- Both components lack rigorous Western safety data
- Not FDA-approved; products in the US are unregulated
This list is not exhaustive. Report anything unexpected to the clinician who prescribed it. If you have severe abdominal pain, trouble breathing, or signs of an allergic reaction, seek care the same day. See also our guide to peptide side effects by class.
A worked example
A 20 mg vial reconstituted with 1 mL of bacteriostatic water gives 20 mg/mL. A 500 mcg dose is then 0.025 mL — about 2.5 units on a 100-unit insulin syringe, giving roughly 40 doses per vial before accounting for residual volume left in the vial and syringe.
Prefer paper? Download the printable Selank + Semax dosing chart (PDF) — every vial size and water volume in syringe units, with the same review byline as this page. All charts →
Commonly cited dose range
Figures circulating for Selank + Semax run from 250 mcg to 1000 mcg. Often administered intranasally in community use. Figures shown are community reference amounts. There is no established or approved dose for either component or the combination.
Read this as reference information, not instruction. These numbers describe what is commonly discussed, not what is right for any individual. Dose, frequency, and whether to use Selank + Semax at all are decisions for a licensed clinician who knows your history.
Common questions
Why combine Selank and Semax?
They are paired on the theory that Selank reduces anxiety while Semax supports focus and cognition — complementary nootropic effects. Neither is FDA-approved, and the combination has no clinical evidence.
Is this blend approved in the US?
No. Both components are approved only in Russia, not by the FDA, and the combination has not been studied.