Thymalin / Thymulin calculator
Thymic peptides studied for immune modulation, popular in longevity protocols. Evidence is largely regional; thymulin itself is not available as an approved drug.
Also known as: Thymic peptide, Thymalin bioregulator
FDA status — not an approved drug Not FDA-approved for any use. Thymalin and thymulin are thymic peptides sold as research or supplement products and are not reviewed by FDA.
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What Thymalin / Thymulin is
Thymalin and thymulin are peptides associated with the thymus gland, which governs immune maturation and shrinks with age. They are used in longevity protocols on the theory that restoring thymic signaling supports immune function. Evidence is largely regional and not independently replicated in large trials.
Research depth: 2/5 Regional human studies with a long-running cohort, but no large rigorous or Western trials. Human trials: Regional studies only. This measures how much has been studied — counting animal and laboratory work — not whether it works for you.
How Thymalin / Thymulin works
Thymic peptides influence the development and activity of T-cells, the immune cells that coordinate defense against infection and abnormal cells. Thymulin's activity depends on binding zinc. The proposed anti-aging rationale is that supplementing thymic signals compensates for age-related thymic involution, but this is not established by rigorous research.
Thymalin / Thymulin side effects
Commonly reported
- Generally reported as well tolerated in regional literature
- Injection-site reactions
- No robust Western safety data
Serious — seek medical care
- Immune modulation is a theoretical concern in autoimmune disease
- Evidence base is thin and not independently replicated
- Quality and purity vary widely among suppliers
This list is not exhaustive. Report anything unexpected to the clinician who prescribed it. If you have severe abdominal pain, trouble breathing, or signs of an allergic reaction, seek care the same day. See also our guide to peptide side effects by class.
A worked example
A 20 mg vial reconstituted with 1 mL of bacteriostatic water gives 20 mg/mL. A 20000 mcg dose is then 1 mL — about 100 units on a 100-unit insulin syringe, giving roughly 1 doses per vial before accounting for residual volume left in the vial and syringe.
Prefer paper? Download the printable Thymalin / Thymulin dosing chart (PDF) — every vial size and water volume in syringe units, with the same review byline as this page. All charts →
Commonly cited dose range
Figures circulating for Thymalin / Thymulin run from 10000 mcg to 30000 mcg. Thymic bioregulators are typically dosed in milligrams in short courses. Figures shown are community reference amounts in micrograms. There is no established or approved dose.
Read this as reference information, not instruction. These numbers describe what is commonly discussed, not what is right for any individual. Dose, frequency, and whether to use Thymalin / Thymulin at all are decisions for a licensed clinician who knows your history.
Common questions
Are thymalin and thymulin the same?
They are related but distinct thymic peptides. Thymalin is a thymic extract/peptide used in Russia; thymulin is a specific zinc-dependent thymic hormone. They are grouped together as thymic immune peptides.
Is there evidence they slow aging?
A small, long-running regional study of thymalin reported improved markers and reduced mortality, but this has not been replicated in large rigorous trials. Evidence is limited.