Thymosin Alpha-1 calculator
An immune-modulating peptide approved in some countries for hepatitis and as a vaccine adjuvant, but not in the United States.
Also known as: Ta1, Zadaxin, Thymalfasin
FDA status — not an approved drug Not FDA-approved in the United States. Thymosin alpha-1 (thymalfasin) is approved in some other countries under the name Zadaxin for hepatitis B and C and as a vaccine adjuvant.
This draw does not fit the selected syringe.213.3 units exceeds the 100-unit barrel. Choose a larger syringe, use less bacteriostatic water, or split the dose.
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What Thymosin Alpha-1 is
Thymosin alpha-1 is a 28-amino-acid peptide originally isolated from the thymus gland. It modulates immune responses and is approved in numerous countries (as Zadaxin) for hepatitis B and C and to boost vaccine response. It is not FDA-approved in the United States.
Research depth: 4/5 Approved in multiple countries with a substantial human trial record, though not in the US. Human trials: Approved abroad, not US. This measures how much has been studied — counting animal and laboratory work — not whether it works for you.
How Thymosin Alpha-1 works
It acts on toll-like receptors and promotes the maturation and function of T-cells and dendritic cells, enhancing the immune system's ability to respond to infection and abnormal cells. This immune-enhancing activity is the basis for its approved uses abroad and its study in sepsis and cancer.
Thymosin Alpha-1 side effects
Commonly reported
- Injection-site redness or discomfort
- Mild flu-like symptoms
- Generally well tolerated in trials
Serious — seek medical care
- Immune stimulation is a theoretical concern in autoimmune disease
- Caution in immunosuppressed transplant recipients
- Not FDA-approved — products sold in the US are unregulated
This list is not exhaustive. Report anything unexpected to the clinician who prescribed it. If you have severe abdominal pain, trouble breathing, or signs of an allergic reaction, seek care the same day. See also our guide to peptide side effects by class.
A worked example
A 3 mg vial reconstituted with 2 mL of bacteriostatic water gives 1.5 mg/mL. A 3200 mcg dose is then 2.133 mL — about 213.3 units on a 100-unit insulin syringe, giving roughly 0 doses per vial before accounting for residual volume left in the vial and syringe.
Prefer paper? Download the printable Thymosin Alpha-1 dosing chart (PDF) — every vial size and water volume in syringe units, with the same review byline as this page. All charts →
Commonly cited dose range
Figures circulating for Thymosin Alpha-1 run from 1600 mcg to 6400 mcg. In countries where it is approved, the typical amount is dosed by body weight or as a fixed amount twice weekly. Figures reflect published regimens. There is no US-approved labeling.
Read this as reference information, not instruction. These numbers describe what is commonly discussed, not what is right for any individual. Dose, frequency, and whether to use Thymosin Alpha-1 at all are decisions for a licensed clinician who knows your history.
Common questions
Is thymosin alpha-1 approved in the US?
No. It is approved in a number of other countries as Zadaxin for hepatitis and immune support, but the FDA has not approved it for any use.
What does thymosin alpha-1 do?
It modulates immune function, enhancing T-cell responses. It has been studied in hepatitis, sepsis, and as a vaccine booster, with mixed results.